Lone Wolf & Cub Manga Omnibus Volume 2 collects two stories from volume 3, volume 4, and three stories from volume 5 and features story by Kazuo Koike and art by Goseki Kojima.

Ronin samurai Ogami Itto and his young son travel a dark road, beset by enemies sworn to destroy them. But how did the Shogun's loyal and trusted executioner become a dishonored fugitive marked for death? What hidden forces moved to destroy Ogami's family and fuel his relentless quest for retribution?